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The Role of Hypoxia-Inducible Factor-2α in Intestinal Iron Absorption

✍ Scribed by Anderson, Erik R. ;Taylor, Matthew ;Shah, Yatrik

Book ID: 122280957
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 39 KB
Volume: 140
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(11)62906-5

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## Abstract Dendritic cells (DC) are the most potent antigen‐presenting cells and during their life cycle they are exposed to different oxygen tensions. Similarly to inflamed and tumor tissues, lymphoid organs are characterized by a hypoxic microenvironment; thus, the modality by which hypoxia may