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Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling

✍ Scribed by Ryan C. Riddle; Richa Khatri; Ernestina Schipani; Thomas L. Clemens

Publisher
Springer
Year
2009
Tongue
English
Weight
181 KB
Volume
87
Category
Article
ISSN
0946-2716

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✍ Antonella Naldini; Emilia Morena; Annalisa Pucci; Diego Miglietta; Elena Riboldi 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 434 KB

## Abstract Dendritic cells (DC) are the most potent antigen‐presenting cells and during their life cycle they are exposed to different oxygen tensions. Similarly to inflamed and tumor tissues, lymphoid organs are characterized by a hypoxic microenvironment; thus, the modality by which hypoxia may