This study was undertaken to distinguish between normal and diabetic subjects by lectin-glycated hemoglobin interaction. The quantitative precipitin method was performed for the interaction between glucosespecific lectin Concanavalin A (Con A) and the glucose-containing RBC-lysate for the estimation
The role of glycation in aging and diabetes mellitus
β Scribed by M. A. M. Boekel
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 658 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0301-4851
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β¦ Synopsis
One of the hypotheses trying to explain the process of aging is the idea of glycation of proteins. This reaction, also called the Maillard or browning reaction, may explain age-related symptoms such as cataract, atherosclerosis and modification of collagen-containing tissues. Diabetics, which posses elevated blood sugar levels, show signs of accelerated aging exposing similar complications. The Maillard reaction, which occurs on a large scale in vivo, may play a key role in the initiation of these symptoms.
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