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The role of gene deletion in the immunoglobulin heavy chain switch

โœ Scribed by Rabbitts, T. H.; Forster, A.; Dunnick, W.; Bentley, D. L.

Book ID
109717383
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
851 KB
Volume
283
Category
Article
ISSN
0028-0836

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Defining the breakpoint of a multigene d
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โœ Zhi-Qiing Chen; Marten H. Hofker; Diane W. Cox ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 455 KB

The constant region of the human immunoglobulin heavy chain (IGHC) is encoded by a cluster of genes near the telomere of chromosome 14q. Deletions and duplications of single or multiple genes in the cluster have been identified, but little information about the breakpoint junctions has been availabl