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The role of G196A polymorphism in the brain-derived neurotrophic factor gene in the cause of Parkinson’s disease: a meta-analysis

✍ Scribed by Elias Zintzaras; Georgios M. Hadjigeorgiou

Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
216 KB
Volume
50
Category
Article
ISSN
1435-232X

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## Abstract The presynaptic dopamine transporter in nigral dopaminergic neurons confers susceptibility to the cytotoxic effects of the neurotoxic metabolite of 1‐methy1‐4‐phenyl‐1,2,3,6‐tetrahydropyridine. Polymorphisms in the dopamine transporter might influence the susceptibility to such toxins.