Fas and Fas ligand-mediated apoptosis an
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Signore, Alberto ;Annovazzi, Alessio ;Gradini, Roberto ;Liddi, Roberto ;Ruberti,
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Article
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1998
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John Wiley and Sons
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English
โ 229 KB
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The relationship between Fas-mediated apoptosis and Type 1 diabetes is currently under investigation. Fas/Fas ligand interaction could be involved both in the insulitis process and in beta-cell death. Nevertheless, different mechanisms appear to be involved in human Type 1 diabetes and in NOD mice.