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The Role of Fas in Autoimmune Diabetes

โœ Scribed by Alexander V Chervonsky; Yi Wang; F.Susan Wong; Irene Visintin; Richard A Flavell; Charles A Janeway Jr.; Louis A Matis

Book ID
117267183
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
598 KB
Volume
89
Category
Article
ISSN
0092-8674

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Fas and Fas ligand-mediated apoptosis an
Fas and Fas ligand-mediated apoptosis and its role in autoimmune diabetes
โœ Signore, Alberto ;Annovazzi, Alessio ;Gradini, Roberto ;Liddi, Roberto ;Ruberti, ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 229 KB ๐Ÿ‘ 1 views

The relationship between Fas-mediated apoptosis and Type 1 diabetes is currently under investigation. Fas/Fas ligand interaction could be involved both in the insulitis process and in beta-cell death. Nevertheless, different mechanisms appear to be involved in human Type 1 diabetes and in NOD mice.