FAS-FAS ligand interaction has been implicated in increased enterocyte apoptosis seen in immune-mediated bowel injury. However, scant information exists on the role of FAS in physiological enterocyte turnover. In the present study, the regulation of enterocyte FAS and FAS ligand expression by cytoki
โฆ LIBER โฆ
The role of fas in apoptosis induced by anticancer drugs
โ Scribed by Alastair Watson
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 29 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0270-9139
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Background and Objectives: Fas (APO-1) induces apoptosis after binding Fas ligand (FasL). Evidence suggests that tumors may use this interaction to evade the host immune response. Fas/FasL expression has not been reported in esophageal cancer. We hypothesized that Fas expression would render esophag