Peroxyacetyl nitrate (PAN), an ubiquitous air pollutant, induced apoptosis in human leukemia HL-60, human chronic myelogenous leukemia K-562, and mouse monocyte-macrophage RAW 264.7 cell lines. In the HL 60 cells, characteristic apoptosis morphology could be observed 4 h after the cells were treated
β¦ LIBER β¦
ChemInform Abstract: Mechanism of DNA Damage and Apoptosis Induced by Anticancer Drugs Through Generation of Reactive Oxygen Species
β Scribed by Hideki Mizutani
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 15 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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## KEY WORDS Allyl isothiocyanate (AITC) has been used as a food additive for paste-type wasallyl isothiocyanate abi (Japanese horseradish) and karashi (Japanese mustard) almost only in Japan, DNA damage even though it has been reported to be carcinogenic and mutagenic. In the reactive oxygen spec
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