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The role of Ets family transcription factor PU.1 in hematopoietic cell differentiation, proliferation and apoptosis

✍ Scribed by Oikawa, Tsuneyuki; Yamada, Toshiyuki; Kihara-Negishi, Fumiko; Yamamoto, Hitomi; Kondoh, Nobuo; Hitomi, Yoshiaki; Hashimoto, Yoshiyuki

Book ID: 110015932
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 194 KB
Volume: 6
Category: Article
ISSN: 1350-9047
DOI: 10.1038/sj.cdd.4400534

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## Abstract Transcription factor Ets‐1 is induced in endothelial cells (ECs) by angiogenic factors, and promotes angiogenesis by inducing angiogenesis‐related genes such as MMPs and integrin β3. Here, we examined the effect of Ets‐1 on apoptosis in ECs. Overexpression of Ets‐1 in human umbilical ve

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