The role of eukaryotic initiation factor 5A in the control of cell proliferation and apoptosis

Evidences of a role for eukaryotic trans

Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation

✍ Lucas T. Parreiras-e-Silva; Augusto D. Luchessi; Rosana I. Reis; Constance Olive 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 325 KB

## Abstract Eukaryotic translation initiation factor 5A (eIF5A) has a unique character: the presence of an unusual amino acid, hypusine, which is formed by post‐translational modifications. Even before the identification of hypusination in eIF5A, the correlation between hypusine formation and prote

Involvement of eukaryotic translation in

Involvement of eukaryotic translation initiation factor 5A (eIF5A) in skeletal muscle stem cell differentiation

✍ Augusto D. Luchessi; Tavane D. Cambiaghi; Sandro M. Hirabara; Rafael H. Lambertu 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 373 KB

## Abstract The eukaryotic translation initiation factor 5A (eIF5A) contains a special amino acid residue named hypusine that is required for its activity, being produced by a post‐translational modification using spermidine as substrate. Stem cells from rat skeletal muscles (satellite cells) were

Loss of the eukaryotic initiation factor

Loss of the eukaryotic initiation factor 3f in melanoma

✍ Adriana Doldan; Anupama Chandramouli; Reneé Shanas; Achyut Bhattacharyya; Stanle 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB

## Abstract Aberrant regulation of the translation initiation is known to contribute to tumorigenesis. eIF3 plays an important role in translation initiation. eIF3f is the p47 subunit of the eIF3 complex whose function in cancer is not clear. Initial studies from our group indicated that eIF3f expr

Thermal killing of human colon cancer ce

Thermal killing of human colon cancer cells is associated with the loss of eukaryotic initiation factor 5A

✍ Alexander Gosslau; David Li-en Jao; Renee Butler; Alice Y.-C. Liu; Kuang Yu Chen 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 463 KB 👁 1 views

## Abstract Heat‐induced cell death appears to be a cell‐specific event. Chronic heat stress was lethal to human colon cancer cells (Caco‐2, HT29, and HCT116), but not to normal diploid fibroblasts and other cancer cells (BJ‐T, WI38, HeLa, ovarian 2008, WI38VA). Acute heat stress (45–51°C, 30 min)

Loss of the eukaryotic initiation factor

Loss of the eukaryotic initiation factor 3f in pancreatic cancer

✍ Adriana Doldan; Anupama Chandramouli; Reneé Shanas; Achyut Bhattacharyya; John T 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 399 KB

## Abstract Aberrant regulation of the translation initiation is known to contribute to tumorigenesis. eIF3 plays an important role in translation initiation. eIF3f is the p47 subunit of the eIF3 complex whose function in cancer is not clear. Initial studies from our group indicated that eIF3f expr

Epidermal growth factor: the driving for

Epidermal growth factor: the driving force in initiation of RPE cell proliferation

✍ Kerstin Steindl-Kuscher; Michael E. Boulton; Paulina Haas; Astrid Dossenbach-Gla 📂 Article 📅 2011 🏛 Springer-Verlag 🌐 English ⚖ 247 KB