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The role of endoplasmic reticulum stress in the early stage of diabetic retinopathy

โœ Scribed by Bin Li; Hong Sheng Wang; Gui Gang Li; Min Jian Zhao; Min Hong Zhao


Publisher
Springer
Year
2009
Tongue
English
Weight
418 KB
Volume
48
Category
Article
ISSN
0940-5429

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The unfolded protein response (UPR) is an evolutionarily conserved cell signaling pathway that is activated to regulate protein synthesis and restore homeostatic equilibrium when the cell is stressed from increased client protein load or the accumulation of unfolded or malfolded proteins. Once activ