The effect of atropine on kindling the amygdala of rats was tested by administering the drug in a dose of 25 mg/kg 1 h before each stimulus was applied. Rats tested with atropine kindled at the same rate as saline-treated controls. Cholinergic activity in the amygdala of rats was assessed, 4 weeks a
Role of Endoplasmic Reticulum Stress in the Amygdaloid Kindling Model of Rats
โ Scribed by Yuri Chihara; Yuto Ueda; Taku Doi; L. James Willmore
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 406 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy. Treatment with intracerebroventricular KYA (360 nmoles (adult dose) or 240 nmoles (prepuhescent dose))
One hundred-four Wistar rats were implanted with a bipolar electrode aimed at the right baso!ateral amygdala, and stimulated bipolarly twice daily (interval between stimulations 30 rain) with a 150 uA, 4-s train of biphasic square-wave l-ms pulses (100 pulses/s). Seventy-four animals developed a sti