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The role of dopamine D1-receptors in morphine-induced hyperlocomotion in mice

✍ Scribed by Funada, Masahiko; Suzuki, Tsutomu; Misawa, Miwa


Book ID
123469943
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
369 KB
Volume
169
Category
Article
ISSN
0304-3940

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Dopaminergic D-1 receptors: essential ro
✍ R. Longoni; L. Spina; G. Chiara πŸ“‚ Article πŸ“… 1987 πŸ› Springer 🌐 English βš– 189 KB

Administration of morphine HC1 (20 mg/kg SC) to male C57BI/6 mice evoked hypermotility. Pretreatment with low doses of the specific D-1 antagonist SCH 23390 (0.006, 0.012, 0.025 mg/kg SC) dose-dependently inhibited morphine-evoked hypermotility. The results suggest that dopamine is the essential med