The role of cytosine arabinoside maintenance in acute nonlymphoblastic leukemia
โ Scribed by P. N. Grozea; Dr. R. H. Bottomley; M. T. Shaw; H. Tu; R. E. Chanes; P. T. Condit
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 394 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0008-543X
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Seven patients with a myelodysplastic syndrome or "smoldering" acute myelogenous leukemia were treated with cytosine arabinoside in low dosage. Four patients experienced transient, partial responses characterized by improved peripheral blood counts, cessation of transfusion requirements, and a decre
Courses of cytosine arabinoside followed by L-asparaginase were administered for 4 days each to 17 children with previously treated acute lymphatic leukemia, at 14to 27-day intervals. Complete or partial remission occurred in 81% of patients after the third or fourth course of therapy. Rlaintenance