Cytosine arabinoside: Results of a cooperative study in acute childhood leukemia
โ Scribed by John P. Howard; Vincent Albo; William A. Newton Jr.
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- English
- Weight
- 334 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Thirteen leukemic patients with disease refractory to conventional chemotherapy were treated with 1.0 to 7.5 g/m2 of Cytosine Arabinoside (Ara-C) over 29 drug cycles. Drug infusions were spaced at 12-hour intervals; a maximum of four doses was administered over 36 hours. After single dose tolerance
Eighteen children with acute myeloid leukemia have been treated with a fourdrug protocol using cytosine arabinoside, daunorubicin, prednisolone, and mercaptopurine or thioguanine. The initial remission rate overall was 78%. Of 15 children who completed a week's treatment, i.e. one complete cycle, 14