The role of cytokines, CTLA-4 and costimulation in transplant tolerance and rejection
โ Scribed by Zhenhua Dai; Fadi G Lakkis
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 54 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0952-7915
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โฆ Synopsis
Abbreviations
CD40L
CD40 ligand CTL cytotoxic T lymphocyte HSA heat-stable antigen ICOS inducible costimulator IFN-ฮณ ฮณ interferon ฮณ IFN-ฮณ ฮณR IFN-ฮณ receptor
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## Abstract ## Objective The precipitating event(s) that triggers Wegener's granulomatosis (WG) is unknown. Cytokines, costimulatory molecules, and counterregulatory molecules control the quality and intensity of immune responses. Thus, they are relevant candidates for genetic studies of immune dy