๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The Role of Cystine-Glutamate Exchange in Nicotine Dependence in Rats and Humans

โœ Scribed by Lori A. Knackstedt; Steven LaRowe; Pascale Mardikian; Robert Malcolm; Himanshu Upadhyaya; Sarra Hedden; Athina Markou; Peter W. Kalivas


Book ID
119198087
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
541 KB
Volume
65
Category
Article
ISSN
0006-3223

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


The Role of Trait Anxiety in Nicotine De
โœ Janet Audrain; Caryn Lerman; Andres Gomez-Caminero; Neal R. Boyd; C. Tracy Orlea ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Bellwether Publishing ๐ŸŒ English โš– 746 KB
L-lactate inhibits L-cystine/L-glutamate
โœ Yutaka Koyama; Yuji Kimura; Hitoshi Hashimoto; Toshio Matsuda; Akemichi Baba ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 106 KB

In several brain pathologies, the level of brain L-lactate increases. The stimulation of L-lactate production is a detrimental factor in promoting neuronal cell damage and astrocytic dysfunction. Astrocytic glutathione metabolism has an important role to protect brain cells against oxidative stress.

Regulation of the System xโˆ’C cystine/glu
โœ Todd Michael Seib; Sarjubhai Amratbhai Patel; Richard James Bridges ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 692 KB

The system x 2 C (Sx 2 C ) transporter functions to mediate the exchange of extracellular cystine (L-Cys 2 ) and intracellular glutamate (L-Glu). Internalized L-Cys 2 serves as a ratelimiting precursor for the biosynthesis of glutathione (GSH), while the externalized L-Glu can contribute to either e