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The role of COX-1 and COX-2 isozymes in experimental cholera

โœ Scribed by Gessell-Lee, Deborah L.; Peterson, Johnny W.


Book ID
124145341
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
189 KB
Volume
120
Category
Article
ISSN
0016-5085

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A comparative study of the COX-1 and COX
โœ Shunzhou Wan; Peter V. Coveney ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 968 KB

## Abstract The monotopic proteins COXโ€1 and โ€2 in dimeric form bound to lipid bilayer membranes are studied using molecular dynamics simulations within an aqueous environment. The 25โ€ns simulations are performed for both isozymes with arachidonic acid bound in the cyclooxygenase sites. The interac