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The role of complement in the pathogenesis of dextran sulfate sodium induced colitis

✍ Scribed by Jennifer Schepp-Berglind; Carl Atkinson; Stephen Tomlinson

Book ID
113805068
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
73 KB
Volume
47
Category
Article
ISSN
0161-5890

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## Background: In this study we determined the consequence of the absence of each tnf receptor, tnfr1 or tnfr2, in the dextran sulfate sodium (dss) model of colitis. ## Methods: Wildtype (wt), tnfr1(-/-) and tnfr2(-/-) mice were fed 3% w/v dss in drinking water for 5 days followed by 2 (day 7) or