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Role of group IIA phospholipase A2 in rat colitis induced by dextran sulfate sodium

✍ Scribed by Yasuhiko Tomita; Hirokuni Jyoyama; Mika Kobayashi; Kenji Kuwabara; Shingo Furue; Masahiko Ueno; Katsutoshi Yamada; Takashi Ono; Isao Teshirogi; Kouji Nomura; Hitoshi Arita; Isao Okayasu; Yozo Hori

Book ID
114015729
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
689 KB
Volume
472
Category
Article
ISSN
0014-2999

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## Background: In this study we determined the consequence of the absence of each tnf receptor, tnfr1 or tnfr2, in the dextran sulfate sodium (dss) model of colitis. ## Methods: Wildtype (wt), tnfr1(-/-) and tnfr2(-/-) mice were fed 3% w/v dss in drinking water for 5 days followed by 2 (day 7) or