## Abstract The proliferation and maturation of granulocytic‐monocytic stem cells appears to be controlled by a series of closely related glycoproteins termed “colony‐stimulating factors” (CSFs). Recently, we devised a 6‐step scheme for the purification of murine fibroblast (L‐cell)‐derived CSF. Te
The Role of Colony Stimulating Activity in Modulating Murine Diffusion Chamber Granulopoiesis
✍ Scribed by Richard Sullivan; Kenneth S. Zuckerman; Peter J. Quesenberry
- Book ID
- 114709252
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 585 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0007-1048
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📜 SIMILAR VOLUMES
Serum obtained from irradiated mice lost its colony stimulating activity when incubated with normal marrow cells. The loss of activity appeared to be due to absorption or inactivation of the active factor in the serum rather than to production of an inhibitor by the cells. METHODS CR strain mice (Ca
## Abstract Adherent stromal cells from mouse bone marrow inhibited the formation of granulocyte/monocyte (G/M) colonies induced in vitro by colony‐stimulating factor (CSF), This inhibition occurred both when crude conditioned media obtained from various sources were used to induce colony formation