## Abstract An analysis was made of some of the processes involved in the stimulation by colony stimulating factor (CSF) of cluster and colony formation by mouse bone marrow cells in agar cultures __in vitro__. Colony formation was shown to be related to the concentration and not the total amount o
Studies on the regulation of granulopoiesis. V. Effect of marrow cells on colony stimulating activity in serum
✍ Scribed by Alec Morley; Kevin A. Rickard; Peter Quesenberry; Marianne Garrity; Frederick Stohlman Jr
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 296 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
Serum obtained from irradiated mice lost its colony stimulating activity when incubated with normal marrow cells. The loss of activity appeared to be due to absorption or inactivation of the active factor in the serum rather than to production of an inhibitor by the cells. METHODS CR strain mice (Carworth) were used for all experiments. Virgin females 12-16
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