## Background: Detection of genetic changes in the mucosa of the upper aerodigestive tract may provide a target for the screening of cytologic specimens to identify premalignant transformation in this region. in this pilot study, the feasibility of the fluorescence in situ hybridization (fish) tech
The role of chromosomal aberrations in premalignant and malignant lesions in head and neck squamous cell carcinoma
β Scribed by Kamal-Eldin Ahmed Abou-Elhamd; Tito Naeem Habib
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 269 KB
- Volume
- 265
- Category
- Article
- ISSN
- 0302-9530
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Alterations in chromosomal number and structure are found in most solid malignancies including head and neck squamous cell carcinoma (HNSC), however, the presence of ongoing, chromosomal instability in HNSC and its relation to spindle assembly checkpoint defects has not been formally de
## Background: Serine proteases have important roles in tumor invasion and metastasis, and their inhibitors, serine protease inhibitors (serpins), are attractive targets for therapeutic strategies. on chromosome 18q21, there is a cluster of serpins: maspin, headpin, and squamous cell carcinoma anti
## Abstract One hundred fiftyβnine patients with squamousβcell carcinoma of the oral cavity, oropharynx, nasopharynx, hypopharynx, and supraglottic larynx, and with clinically negative neck (Stage NO) were reviewed to determine the value of elective neck irradiation (ENI). The primary cancer was co
## Abstract Metalloproteins are a group of catalytic proteins, which play significant roles in cell cycle and death. Matrix metalloproteinases (MMPs) are a family of endopeptidases that are capable of digesting extracellular matrix components. They have been implicated in carcinogenesis and recent