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The role of CD8 T cell and its receptor change in Alzheimer's disease

✍ Scribed by Chuanhai Cao; Xiaoyang Lin; Wenshi Wang; Yaqiong Li; Jianfeng Cai; Balaibail Raj; Huntington Potter


Book ID
118468631
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
60 KB
Volume
8
Category
Article
ISSN
1552-5260

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CD4, CD8 and the role of CD45 in T-cell
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CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta