Presentation of viral antigens to T cells does not require uptake by 'professional' antigen-presenting cells. Viruses have specialized to enter the cells in which they replicate. Virus entry, uncoating and new viral protein synthesis can load both the cytosolic and the endosomal pathway of antigen p
The role of CD4+and CD8+T cells in controlling HIV infection
β Scribed by Stephen A. Migueles; Mark Connors
- Book ID
- 107542166
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 404 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1523-3847
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Peripheral blood mononuclear cells were prepared from human immunodeficiency virus-positive (HIV Ψ ) individuals (n β«Ψβ¬ 46) to investigate the expression of both chains of the interleukin-2 receptor. Both qualitative and quantitative changes in expression were observed. Total lymphocyte expression o