CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta
✦ LIBER ✦
The role of CD45 in T-cell activation — resolving the paradoxes?
✍ Scribed by Denis Alexander; Masahiro Shiroo; Anne Robinson; Mark Biffen; Emer Shivnan
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 512 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
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