The role of calcium in macrophage chemotaxis to the phorbol ester tumor promoter TPA
β Scribed by Bonita M. Smith; Fay K. Kessler; Susan H. Carchman; Richard A. Carchman
- Book ID
- 113236116
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 747 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0143-4160
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Lβcell colonyβstimulating factor (CSFβ1) is a sialoglycoprotein of molecular weight 70,000 daltons that specifically stimulates macrophage colony formation by single committed cells from normal mouse bone marrow and by various classes of more differentiated tissueβderived mononuclear ph
Treatment of murine peritoneal exudate macrophages (PEM) by tumor-prornoting phorbol esters (TPA) results in a rapid loss of binding activity to radioactive-labeled colony-stimulating factor ([1251]-CSF-1) on the cell surface. The inhibitory effect of TPA on PEM i s transient; treated cells recover