The role of BAFF in immune function and implications for autoimmunity
β Scribed by Susan L. Kalled
- Book ID
- 110746576
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 485 KB
- Volume
- 204
- Category
- Article
- ISSN
- 0105-2896
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The TNF family ligands BAFF (also called BLyS) and APRIL regulate lymphocyte survival and activation. BAFF binds to three receptors, BAFF-R, TACI and BCMA, whereas APRIL interacts with TACI, BCMA and proteoglycans. The contribution of BAFF and APRIL to B-cell and plasma-cell survival, CD154 (CD40L)-
GCD4\* + CDEI' WCW4' + CDB' ' cells, including macrophagw and IymphwyteP, have the capacity b prodwe TGF-P, and virtually a,, cell hjpes express hiahaffinihr ,e&ive,y activates CDS-T rd,s ,a ~mliferate", and a"g",c",r the maturatio" of T tells ,mm naive LO activated or memos crw. The regulabry effec