The role of antibody and complement in lysing virus-infected cells
β Scribed by J. G. P. Sissons; R. D. Schreiber; N. R. Cooper; M. B. A. Oldstone
- Publisher
- Springer-Verlag
- Year
- 1982
- Tongue
- English
- Weight
- 373 KB
- Volume
- 170
- Category
- Article
- ISSN
- 0300-8584
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Sera collected from patients with acute hepatitis A virus (HAV) infection and convalescent sera were examined for cytolytic activity against HAV-infected human-embryo lung fibroblasts (HAV carrier fibroblasts). Using the 51chromium release assay, no complement dependent antibody mediated cytolytic a
## Abstract HIVβ1βpositive antisera were tested for their ability to lyse HIVβ1βinfected cells in the presence of active complement. Cytolytic effects caused by sera derived from infected humans were slower than those observed with sera from immunised chimpanzees. Lytic but also negative sera were