An understanding of the natural history of changes in prostate-specific antigen (PSA) may be valuable as a surrogate view of prostate dynamics, as a method to differentiate between benign and malignant growth, and as a means to assess the use of PSA as a tool for monitoring activity of chemopreventi
The role of angiogenesis in prostate development and the pathogenesis of prostate cancer
โ Scribed by David Hrouda; David Nicol; Robert Gardiner
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 224 KB
- Volume
- 30
- Category
- Article
- ISSN
- 2194-7228
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Serum prostatic specific antigen (PA) and prostatic acid phosphatase (PAP) levels were measured in 113 untreated patients with prostatic cancer and in 137 patients with benign prostatic hypertrophy (BPH). Of the 113 cancer patients, 81% and 69%, respectively, were detectable by means of PA or PAP as
## BACKGROUND. A variety of innovative approaches to the prevention of prostate cancer are now available, including selenium, alpha tocopherol, dietary interventions, and vitamin D. Perhaps the most promising opportunity is based upon considerable evidence that cumulative androgen exposure of the