The role of active-site residues in naphthalene dioxygenase
โ Scribed by Rebecca E. Parales
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 398 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1476-5535
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๐ SIMILAR VOLUMES
## Abstract The enzymes of the thioredoxin family fulfill a wide range of physiological functions. Although they possess a similar CXYC active site motif, with identical environment and stereochemical properties, the redox potential and p__K__~a~ of the cysteine pair varies widely across the family
Understanding the role of active-site residues in enzymatic catalysis is of fundamental importance for a microscopic description of the catalytic mechanism, but also for the design of effective enzyme mimics or improvement of existing enzymes (or abzymes) for catalyzing chemical reactions. Site-dire