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The Role of Acetaldehyde in the Central Effects of Ethanol

✍ Scribed by Etienne Quertemont; Kathleen A. Grant; Mercè Correa; Maria N. Arizzi; John D. Salamone; Sophie Tambour; Carlos M.G. Aragon; William J. McBride; Zachary A. Rodd; Avram Goldstein; Alejandro Zaffaroni; Ting-Kai Li; Milena Pisano; Marco Diana


Book ID
110086854
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
133 KB
Volume
29
Category
Article
ISSN
0145-6008

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Ethanol administration inhibits hepatic protein and glycoprotein secretion. Previous studies have shown that the metabolism of ethanol is required for this effect. Experiments were designed to determine whether acetaldehyde, the first metabolite of ethanol oxidation, mediated the ethanol-induced sec