The role of a conserved histidine residue, His324, in Trigonopsis variabilis D-amino acid oxidase
β Scribed by Long-Liu Lin; Wen-Ching Wang; Sheau-Shya Ju; Hungchien Roger Chien; Wen-Hwei Hsu
- Book ID
- 117519338
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 269 KB
- Volume
- 176
- Category
- Article
- ISSN
- 0378-1097
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## Abstract The inhibition of Dβamino acid oxidase contained in permeabilized cells of the yeast __Trigonopsis variabilis__ by Ξ±βketo acids (pyruvic acid, phenylpyruvic acid and 4βmethylthioβ2βoxobutanoic acid), products of the transformation of the corresponding Dβamino acids, was studied. In all
The industrial importance of Trigonopsis variabilisd-amino acid oxidase (TvDAAO) is represented by its biocatalytic oxidative deamination of cephalosporin C (CPC) to yield glutaryl-7-aminocephalosporanic acid (GL-7-ACA). The process has been incorporated into a two-step bioconversion to produce 7-am