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The role of 1,25-dihydroxyvitamin D3 and parathyroid hormone in the regulation of chick renal 25-hydroxyvitamin D3-24-hydroxylase

✍ Scribed by Yoko Tanaka; Roman S. Lorenc; Hector F. DeLuca


Book ID
115702426
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
491 KB
Volume
171
Category
Article
ISSN
0003-9861

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Regulation of 25-hydroxyvitamin D3-24-hy
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## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu