The revival (or, rather, survival) of disulfiram
✍ Scribed by SANDEEP GROVER; DEBASISH BASU
- Book ID
- 108597046
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 40 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0965-2140
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📜 SIMILAR VOLUMES
The proteasome pathway is an important target for anticancer drug development. Here, we identify the antialcoholism drug disulfiram and its analogue pyrrolidine dithiocarbamate (PDTC) as inhibitors of the 26S proteasome activity in a cell-based screening assay. As expected for proteasome inhibitors,
Retinal survival and revival times were measured in cats and rabbits at controlled retinal temperatures. While the great difference between b-wave survival times in cats and rabbits was confirmed, the revival times were distinctly shorter (30min) than those previously found.