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The revised structure of penstemide

✍ Scribed by S.R. Jensen; B.J. Nielsen; C.B. Mikkelsen; J.J. Hoffmann; S.D. Jolad; J.R. Cole

Publisher: Elsevier Science
Year: 1979
Tongue: French
Weight: 110 KB
Volume: 20
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)95378-x

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✦ Synopsis

The original structure of the antitumor agent, penstemide, has been revised to an sovaleroyl type iridoid glucoside based upon additional physical data.

The isolation and identification of the antitumor agent, penstemide (&) was reported in Tetrahedron Letters, No. 46, pp. 4119-4120 (1976). A reexamination of the physical data along with additional new information necessitates modifying the structure to &.

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