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The retinoid fenretinide inhibits proliferation and downregulates cyclooxygenase-2 gene expression in human colon adenocarcinoma cell lines

✍ Scribed by Greogory Merritt; Elias T. Aliprandis; Francesco Prada; Basil Rigas; Khosrow Kashfi

Book ID: 117466801
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 182 KB
Volume: 164
Category: Article
ISSN: 0304-3835
DOI: 10.1016/s0304-3835(00)00714-x

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## Cyclooxygenase -2 (COX-2), an inducible enzyme that catalyzes the formation of prostaglandins and other eicosanoids from arachidonic acid, is constitutively expressed in several human carcinomas. COX-2 expression, however, has not been extensively studied in leukemia. Human T cell leukemia virus

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