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The results of high energy fast neutron dose optimization studies in the head and neck, thorax, and pelvis

✍ Scribed by T.W. Griffin; T. Pajak; G.E. Laramore; F. Thomas; M. Maor


Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
128 KB
Volume
12
Category
Article
ISSN
0360-3016

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Twenty 36-hour infusions of high-dose methotrexate were given preoperatively to 10 patients with head and neck cancer. Plasma methotrexate levels of greater than 1 X 10(-5) M were maintained for 36 hours and declined with primary and secondary plasma half-lives of 1.7 and 9.2 hours following the end