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The repair of methyl methanesulphonate-induced lesions in the DNA of a murine lymphoma cell

✍ Scribed by P. Karran


Book ID
113135380
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
988 KB
Volume
7
Category
Article
ISSN
0009-2797

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5-Bromodeoxyuridine (BrdU)-induced sister chromatid exchanges (SCEs) are mainly determined during replication on a BrdU-substituted template. The BrdU, once incorporated, is rapidly excised as uracil (U), and the gap is repaired with the incorporation of BrdU from the medium, which leads to further