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Detection and repair of a UV-induced photosensitive lesion in the DNA of human cells

โœ Scribed by Andrew A. Francis; James D. Regan


Book ID
116108133
Publisher
Elsevier Science
Year
1986
Weight
565 KB
Volume
165
Category
Article
ISSN
0167-8817

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Normal human skin fibroblasts were exposed to 0-10 J m-2 of 254 nm UV, incubated 0-16 h and then treated with 0-150 kJ m-2 of sunlamp UV greater than 315 nm. For each treatment, the cells were subjected to alkaline elution in order to measure the yield of single strand breaks (ssb) produced. It was