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The release profile of a controlled release preparation of 5-aminosalicylic acid (Rowasa I®) in humans

✍ Scribed by Robin S. McLeod; Zane Cohen; Barbara J. Vari; Joan E. Blair; Gordon R. Greenberg

Book ID
112679107
Publisher
Springer
Year
1990
Tongue
English
Weight
456 KB
Volume
33
Category
Article
ISSN
0012-3706

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✍ D. K. Yu; B. Morrill; L. S. Eichmeier; D. H. Giesing; S. J. Weir; R. C. Lanman; 📂 Article 📅 1995 🏛 Springer 🌐 English ⚖ 546 KB

One gram single dose of Pentasa controlledrelease capsules was administered to 24 healthy volunteers under fasting condition. Mean plasma 5-aminosalicylic acid (5-ASA) and acetyl 5-ASA concentrations peaked at 0.53 gg' m1-1 and 1.33 gg. m1-1 from 3 to 4 hours following dosing, respectively. The half