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Application of 2-hydroxyethyl methacrylate polymers in controlled release of 5-aminosalicylic acid as a colon-specific drug

✍ Scribed by Mirzaagha Babazadeh; Ladan Edjlali; Lida Rashidian


Book ID
106438390
Publisher
Springer
Year
2007
Tongue
English
Weight
162 KB
Volume
14
Category
Article
ISSN
1022-9760

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## Abstract 4‐{(1E,4E)‐5‐[4‐(Acryloyloxy)phenyl]‐3‐oxopenta‐1,4‐dienyl}phenyl acrylate (APPA) was synthesized by reacting (1E,4E)‐1,5‐bis(4‐hydroxyphenyl)penta‐1,4‐dien‐3‐one (HPD) and acryloyl chloride using triethylamine as a base. 2′,4‐Dichloro‐5′‐fluoro‐1‐ene‐2‐(4‐hydroxyphenyl)phenone (EHP) (A