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The Relationship of the Influenza Virus Inhibitory Activity of Glycoproteins to their Molecular Size and Sialic Acid Content

โœ Scribed by Georg F. Springer, H. Gerhard Schwick and Mary Ann Fletcher


Book ID
123649431
Publisher
National Academy of Sciences
Year
1969
Tongue
English
Weight
324 KB
Volume
64
Category
Article
ISSN
0027-8424

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Thiomethylmercuryl 9-acetamido-9-deoxy-sialoside was prepared and found to inhibit the 9-O-acetylsialic acid esterase from influenza C virus in a competitive manner with a K~ of 4.2+0.5 mM. The inhibitor is being used in the X-ray determination of the crystal structure of the esterase.