✦ LIBER ✦
Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus
✍ Scribed by Wolfgang Fitz; Peter B. Rosenthal; Chi-Huey Wong
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 440 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0968-0896
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✦ Synopsis
Thiomethylmercuryl 9-acetamido-9-deoxy-sialoside was prepared and found to inhibit the 9-O-acetylsialic acid esterase from influenza C virus in a competitive manner with a K~ of 4.2+0.5 mM. The inhibitor is being used in the X-ray determination of the crystal structure of the esterase.