The relationship of the cell surface to metabolism. II. The cell surface of yeast as the site of inhibition of glucose metabolism by uranium
โ Scribed by Rothstein, A. ;Larrabee, C.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1948
- Tongue
- English
- Weight
- 559 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0095-9898
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
I t has been shown by isotope techniques (Rothstein and AIeier, '48) that a number of acid phosphatases are located on the cell surface of yeast. These phosphatases can hydrolyze such substrates as adenosine triphosphate, adenosine diphosphat e, inorganic t riphosphat e and pyrophosphat e, phenyl pl
In the conrse of experiments with liviiig yeast cells, it mas found tliat adenmine triyliosphate (ATP) added to the mecliuin was hydrolyzed to inorganic phosphate plus aderiylic acid. Tlie quantitative recovery of the 1woclncts of lipclrolysis in the inediuxn suggested tliat the phospliate-splittiii
## FOUR FIGURES I n previous papers of this series (Rothstein and Larrabee, '48 ; Rothstein, Frenkel and Larrabee, '48 ; Rothstein, Rleier and Hurwitz, '51; Rothstein and Meier, '51), it has been shown that the uranyl ion specifically inhibits the metabolism of hexoses by forming a highly undissoc