Transforming growth factor-beta 1 (TGF-β
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Giovanni Ferrari; Brandoch D. Cook; Vitaly Terushkin; Giuseppe Pintucci; Paolo M
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Article
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2009
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John Wiley and Sons
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English
⚖ 451 KB
## Abstract VEGF and TGF‐β1 induce angiogenesis but have opposing effects on endothelial cells. VEGF protects endothelial cells from apoptosis; TGF‐β1 induces apoptosis. We have previously shown that VEGF/VEGF receptor‐2 (VEGFR2) signaling mediates TGF‐β1 induction of apoptosis. This finding raised