The relationship between pKa and skin irritation for a series of basic penetrants in man
β Scribed by BERNER, B
- Book ID
- 122366438
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 709 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0272-0590
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In buffered watermethanol media, the pK, values of acidbase equilibria involved in the protonation of substituted quinolines are determined by UV-visible absorption spectrometry. The observed behavior depends on the nature of RP: the N-CH, derivatives exist as quinoline, the N-H derivatives as 44min