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The relationship between increased folate stetabolism and the increased requirement for folate in pregnancy

✍ Scribed by Lynn B. Bailey; Jesse F. Gregory; Marie Caudill; Amelia Cruz


Book ID
111160163
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
41 KB
Volume
108
Category
Article
ISSN
1470-0328

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Folate receptor (FR) has been proposed as a promising target for tumor drug targeting. The aim of this study was to increase the chemo-sensitivity of FR-positive cells to doxorubicin by folate-directed enzyme prodrug therapy (FDEPT). Folate conjugated penicillin-G amidase was prepared and its abilit