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The relationship between dysplasia and mutations of p53: A Ki-ras gene in ulcerative colitis

✍ Scribed by Moon, Cheol; Kim, Jeong Wook; Chang, Sae Kyung


Book ID
122539270
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
165 KB
Volume
114
Category
Article
ISSN
0016-5085

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I-Hydroxyanthraquinone (1-HA), which is present in some herbs, and methylazoxymethanol (MAM) acetate, a metabolite o f azoxymethane, show synergistic carcinogenicity in rat colon, and 1 -HA induces ulcerative changes with simultaneous severe inflammation o f the entire colon. In this study, mutation